The Nanofactory Collaboration project is a cooperative group started by molecular nanotechnology pioneers Dr. Ralph Merkle and Robert Freitas. The project's goal is to create reprogrammable, ~100nm-scale robotic arms and mills, some capable of self-replication, for use in a nanomanufacturing system scalable to the desktop level.

Their site answers the questions, "what is a nanofactory?", and "what is diamondoid", among others. Freitas and Merkle have been been joined by over a dozen collaborators, all working on different nanoscale systems. The Nanofactory Collaboration group is currently seeking additional researchers as well as corporate sponsors.